Apoptosis inducer 9

Catalog No.: A32902
Apoptosis Inducer
Apoptosis Inducer 9 targets the apoptotic pathway to effectively promote cell death via the mitochondrial mechanism. It displays an IC50 value of 4.21 μM, leading to the activation of key apoptotic markers including cleaved caspase-3, cleaved caspase-9, and cleaved PARP. This compound offers substantial potential for the development of novel anti-proliferative agents, making it valuable for cancer research and studies focused on cell death mechanisms.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionApoptosis Inducer 9 targets the apoptotic pathway to effectively promote cell death via the mitochondrial mechanism. It displays an IC50 value of 4.21 μM, leading to the activation of key apoptotic markers including cleaved caspase-3, cleaved caspase-9, and cleaved PARP. This compound offers substantial potential for the development of novel anti-proliferative agents, making it valuable for cancer research and studies focused on cell death mechanisms.
Product Information
Catalog NumA32902
FormulaC34H55N3O4S
Molecular Weight601.88
CAS Number2551067-10-6
SMILESC[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@]4(OC(C)(CCC4)C)C)C)O)([H])[C@@]5([C@@](C(C)([C@H](CC5)OC(CSC6=NN=CN6)=O)C)([H])CC1)C
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