Aristolochic acid A sodium

Catalog No.: A79588
NF-κB Inhibitor
Aristolochic acid A sodium is a potent NF-κB inhibitor derived from Aristolochia and Asarum species. This compound effectively diminishes the activity of both activator protein 1 (AP-1) and NF-κB, thereby modulating key signaling pathways involved in inflammation and cancer. Additionally, Aristolochic acid A sodium has been shown to reduce BLCAP gene expression in human cell lines, making it valuable for research in cell signaling and gene regulation.
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
10mg
$40.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAristolochic acid A sodium is a potent NF-κB inhibitor derived from Aristolochia and Asarum species. This compound effectively diminishes the activity of both activator protein 1 (AP-1) and NF-κB, thereby modulating key signaling pathways involved in inflammation and cancer. Additionally, Aristolochic acid A sodium has been shown to reduce BLCAP gene expression in human cell lines, making it valuable for research in cell signaling and gene regulation.
Product Information
Catalog NumA79588
FormulaC17H10NNaO7
Molecular Weight363.25
CAS Number10190-99-5
SMILESO=C(O[Na])C1=CC2=C(OCO2)C3=C4C(C(OC)=CC=C4)=CC([N+]([O-])=O)=C31
SynonymsAristolochic acid I sodium; TR 1736 sodium
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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