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Esculentoside H

Catalog No.: A40644
NF-κB Inhibitor
Esculentoside H (EsH) is a saponin with inhibitory effects on the NF-κB signaling pathway. It exhibits notable anti-tumor activity, primarily through the modulation of TNF release. EsH has been shown to suppress colon cancer cell migration by inhibiting JNK1/2 and reducing the expression of matrix metalloproteinases-9 (MMP-9), making it a valuable tool for research in cancer biology and therapeutic interventions.
Esculentoside H 66656-92-6 NF-κB Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$90.00
In stock
10mg
$135.00
In stock
25mg
$230.00
In stock
50mg
$325.00
In stock
100mg
$480.00
In stock
200mg
$660.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEsculentoside H (EsH) is a saponin with inhibitory effects on the NF-κB signaling pathway. It exhibits notable anti-tumor activity, primarily through the modulation of TNF release. EsH has been shown to suppress colon cancer cell migration by inhibiting JNK1/2 and reducing the expression of matrix metalloproteinases-9 (MMP-9), making it a valuable tool for research in cancer biology and therapeutic interventions.
Product Information
Catalog NumA40644
FormulaC48H76O21
Molecular Weight989.10
CAS Number66656-92-6
SMILESO=C([C@]1(CC[C@@](C(OC)=O)(C)C2)[C@]2([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(C[C@H](O)[C@H](O[C@@](OC[C@@H](O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)[C@@H]7O)([H])[C@@H]7O)[C@@]5(C)CO)C)[C@]3(C)CC1)O[C@@H]([C@@H]([C@@H](O)[C@@H]8O)O)O[C@@H]8CO
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
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NF-κB/IκB > NF-κB