ASMI is a ratiometric, two-photon excited fluorescent probe that targets mitochondrial cysteine. It features a biocompatible merocyanine fluorophore and an acrylate moiety for selective thiol reactivity. ASMI enables high-contrast, bright imaging of living cells and intact tissues, with a depth of up to 150 μm, facilitating rapid monitoring of cellular redox states. The probe exhibits a two-photon action cross section (Φσmax) of 65.2 GM at an excitation wavelength (λex) of 740 nm, making it suitable for advanced fluorescence microscopy applications.
ASMI is a ratiometric, two-photon excited fluorescent probe that targets mitochondrial cysteine. It features a biocompatible merocyanine fluorophore and an acrylate moiety for selective thiol reactivity. ASMI enables high-contrast, bright imaging of living cells and intact tissues, with a depth of up to 150 μm, facilitating rapid monitoring of cellular redox states. The probe exhibits a two-photon action cross section (Φσmax) of 65.2 GM at an excitation wavelength (λex) of 740 nm, making it suitable for advanced fluorescence microscopy applications.
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