Asperaldin

Catalog No.: A43604
Aldose Reductase Inhibitor
Asperaldin is a potent inhibitor of aldose reductase, an enzyme involved in the polyol pathway that converts glucose to sorbitol. Isolated from Aspergillus niger CFR-1046, Asperaldin has demonstrated significant biological activity in the modulation of diabetic complications and oxidative stress. This compound serves as a valuable tool for research applications aimed at understanding the role of aldose reductase in various metabolic disorders.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAsperaldin is a potent inhibitor of aldose reductase, an enzyme involved in the polyol pathway that converts glucose to sorbitol. Isolated from Aspergillus niger CFR-1046, Asperaldin has demonstrated significant biological activity in the modulation of diabetic complications and oxidative stress. This compound serves as a valuable tool for research applications aimed at understanding the role of aldose reductase in various metabolic disorders.
Product Information
Catalog NumA43604
FormulaC16H18O5
Molecular Weight290.31
CAS Number561297-46-9
SMILESO=C1C=C(C(C2=C1C=C(O)C=C2OCCCCCC)=O)O
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