Asperflavin

Catalog No.: A25534
Anti-inflammatory Agent
Asperflavin is an anti-inflammatory agent derived from the marine fungus Eurotium amstelodami. It effectively inhibits the production of nitric oxide (NO), prostaglandin E2 (PGE2), and proinflammatory cytokines, along with downregulating the expression of inducible nitric oxide synthase (iNOS) in LPS-treated RAW 264.7 cells. Asperflavin serves as a valuable tool in the investigation of inflammatory diseases and their mechanisms.
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5mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAsperflavin is an anti-inflammatory agent derived from the marine fungus Eurotium amstelodami. It effectively inhibits the production of nitric oxide (NO), prostaglandin E2 (PGE2), and proinflammatory cytokines, along with downregulating the expression of inducible nitric oxide synthase (iNOS) in LPS-treated RAW 264.7 cells. Asperflavin serves as a valuable tool in the investigation of inflammatory diseases and their mechanisms.
Product Information
Catalog NumA25534
FormulaC16H16O5
Molecular Weight288.30
CAS Number1415764-41-8
SMILESOC1=C2C(C[C@](O)(CC2=O)C)=CC3=CC(O)=CC(OC)=C31
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