Fig. 1 · Structure
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Aspochalasin D
Antimicrobial Agent
Aspochalasin D is a co-metabolite derived from Aspergillus microcysticus that exhibits antimicrobial properties. This compound demonstrates antibacterial activity against both Gram-positive and Gram-negative bacteria at a concentration of 1 mg/mL. Additionally, Aspochalasin D exhibits cytotoxic effects on Ba/F3-V12 cells, inducing apoptosis with lower IC50 values of 0.49 μg/mL in IL-3-free conditions compared to 1.9 μg/mL in the presence of IL-3. Its unique biological profile makes it a valuable reagent for research in antimicrobial and cytotoxicity studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 71968-02-0 |
| Applications | Antimicrobial Agent |
| Formula | C24H35NO4 |
| Molecular Weight | 401.54 |
| SMILES | O=C1N[C@@H](CC(C)C)[C@]2([H])[C@H](C)C(C)=C[C@@](/C=C(C)/CC[C@@H](O)[C@@H](O)/C=C/3)([H])[C@]12C3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.