Aspochalasin I is a potent tyrosinase inhibitor that effectively suppresses melanogenesis, achieving an IC50 of 22.4 μM. This compound also demonstrates cytotoxic effects against various cancer cell lines, including NCI-H460, MCF-7, and SF-268, with IC50 values of 22.1, 33.4, and 19.9 μM, respectively. Due to its role in inhibiting melanin production, Aspochalasin I can be utilized in research aimed at developing skin whitening agents and exploring therapeutic avenues in cancer treatment.
Aspochalasin I is a potent tyrosinase inhibitor that effectively suppresses melanogenesis, achieving an IC50 of 22.4 μM. This compound also demonstrates cytotoxic effects against various cancer cell lines, including NCI-H460, MCF-7, and SF-268, with IC50 values of 22.1, 33.4, and 19.9 μM, respectively. Due to its role in inhibiting melanin production, Aspochalasin I can be utilized in research aimed at developing skin whitening agents and exploring therapeutic avenues in cancer treatment.
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