Tyrosinase-IN-16 is a potent inhibitor of tyrosinase, exhibiting a Ki value of 470 nM. This compound demonstrates significant cytotoxicity against B16F10 melanoma cells, achieving over 90% inhibition at a concentration of 20 μM. Tyrosinase-IN-16 is valuable for studies investigating mechanisms of melanin synthesis and potential therapeutic applications in pigmentary disorders and melanoma research.
Tyrosinase-IN-16 is a potent inhibitor of tyrosinase, exhibiting a Ki value of 470 nM. This compound demonstrates significant cytotoxicity against B16F10 melanoma cells, achieving over 90% inhibition at a concentration of 20 μM. Tyrosinase-IN-16 is valuable for studies investigating mechanisms of melanin synthesis and potential therapeutic applications in pigmentary disorders and melanoma research.
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