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Autocamtide-3

Catalog No.: A78517
CaMKII Substrate
Autocamtide-3 is a selective substrate for Ca2+/calmodulin-dependent kinase II (CaMKII), characterized by its 13-amino-acid sequence that includes the phosphorylatable residue Thr287. This peptide serves as a valuable tool for studying the activation and regulation of CaMKII in various biological contexts. Its application in research encompasses investigations into calcium signaling, neuronal function, and cardiac physiology.
Autocamtide-3 142828-10-2 CaMKII Substrate
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAutocamtide-3 is a selective substrate for Ca2+/calmodulin-dependent kinase II (CaMKII), characterized by its 13-amino-acid sequence that includes the phosphorylatable residue Thr287. This peptide serves as a valuable tool for studying the activation and regulation of CaMKII in various biological contexts. Its application in research encompasses investigations into calcium signaling, neuronal function, and cardiac physiology.
Product Information
Catalog NumA78517
FormulaC65H113N21O20
Molecular Weight1508.72
CAS Number142828-10-2
Sequence shorteningKKALHRQETVDAL
SMILESCC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)C(C)C)C(O)=O
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Neuronal Signaling > CaMK