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Catalog No.: A11299

β-lactamase inhibitor


Avibactam Chemical Structure

CAS NO. 1192500-31-4

Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor.

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Moonsuk Bae, .et al. In Vitro Activities of Ceftazidime-Avibactam and Aztreonam-Avibactam at Different Inoculum Sizes of Extended-Spectrum β-Lactam-Resistant Enterobacterales Blood Isolates, Antibiotics (Basel), 2021, Dec 5;10(12):1492 PMID: 34943704
  • Taeeun Kim, .et al. In Vitro Activities and Inoculum Effects of Ceftazidime-Avibactam and Aztreonam-Avibactam against Carbapenem-Resistant Enterobacterales Isolates from South Korea, Antibiotics (Basel), 2020, Dec 15;9(12):912 PMID: 33334045
  • Annelien Everaert, .et al. Effect of β-Lactamase inhibitors on in vitro activity of β-Lactam antibiotics against Burkholderia cepacia complex species, Antimicrob Resist Infect Control, 2016, 5: 44 PMID: 27895902

Biological Activity

Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.69 mL 188.47 mL 376.93 mL
0.5 mM 7.54 mL 37.69 mL 75.39 mL
1 mM 3.77 mL 18.85 mL 37.69 mL
5 mM 0.75 mL 3.77 mL 7.54 mL

*The above data is based on the productmolecular weight 265.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11299
Actions Inhibitor
CAS No. 1192500-31-4
Formula C7H11N3O6S
M. Wt 265.3
Purity >98%
SMILES C1C[C@@H](N2C[C@H]1N(C2=O)OS(=O)(=O)O)C(=O)N

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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