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- Moonsuk Bae, .et al. In Vitro Activities of Ceftazidime-Avibactam and Aztreonam-Avibactam at Different Inoculum Sizes of Extended-Spectrum β-Lactam-Resistant Enterobacterales Blood Isolates, Antibiotics (Basel), 2021, Dec 5;10(12):1492 PMID: 34943704
- Taeeun Kim, .et al. In Vitro Activities and Inoculum Effects of Ceftazidime-Avibactam and Aztreonam-Avibactam against Carbapenem-Resistant Enterobacterales Isolates from South Korea, Antibiotics (Basel), 2020, Dec 15;9(12):912 PMID: 33334045
- Annelien Everaert, .et al. Effect of β-Lactamase inhibitors on in vitro activity of β-Lactam antibiotics against Burkholderia cepacia complex species, Antimicrob Resist Infect Control, 2016, 5: 44 PMID: 27895902
Biological Activity
Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.69 mL | 188.47 mL | 376.93 mL |
| 0.5 mM | 7.54 mL | 37.69 mL | 75.39 mL |
| 1 mM | 3.77 mL | 18.85 mL | 37.69 mL |
| 5 mM | 0.75 mL | 3.77 mL | 7.54 mL |
*The above data is based on the productmolecular weight 265.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11299 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1192500-31-4 |
| Formula | C7H11N3O6S |
| M. Wt | 265.3 |
| Purity | >98% |
| SMILES | C1C[C@@H](N2C[C@H]1N(C2=O)OS(=O)(=O)O)C(=O)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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