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AY254

Catalog No.: A23881

PAR2 agonist
AY254 is an analogue of AY77. AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling.
AY254
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AY254 1mg
$759.00
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Biological Activity
Discription AY254 is an analogue of AY77. AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling.
Product Information
Catalog Num A23881
Formula C30H49N9O6
Molecular Weight 631.77
CAS Number 2093408-03-6
Sequence {5-Isoxazolylcarbonyl-Cha}-{Chg}-Ala-Arg-NH2
Sequence shortening {5-Isoxazolylcarbonyl-Cha}-{Chg}-AR-NH2
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GPCR/G Protein > Protease-Activated Receptors (PAR)
Peptides
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