Azide-C2-Azide is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). Functioning through click chemistry, it features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compounds possessing alkyne functionalities. Additionally, Azide-C2-Azide is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing molecules, making it a versatile tool in chemical biology and drug development applications.
Azide-C2-Azide is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). Functioning through click chemistry, it features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compounds possessing alkyne functionalities. Additionally, Azide-C2-Azide is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing molecules, making it a versatile tool in chemical biology and drug development applications.
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