Azido-C2-SS-PEG2-C2-acid is a cleavable polyethylene glycol (PEG) linker designed for use in antibody-drug conjugates (ADCs). It features an azide group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, this linker can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, enabling versatile bioconjugation applications in chemical biology and therapeutic development.
Azido-C2-SS-PEG2-C2-acid is a cleavable polyethylene glycol (PEG) linker designed for use in antibody-drug conjugates (ADCs). It features an azide group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, this linker can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, enabling versatile bioconjugation applications in chemical biology and therapeutic development.
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