Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable linker designed for use in antibody-drug conjugates (ADCs). This 5 unit PEG-based reagent features an azide group that enables its application in click chemistry, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. It is also suitable for strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, facilitating efficient conjugation in the development of targeted therapeutics.
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable linker designed for use in antibody-drug conjugates (ADCs). This 5 unit PEG-based reagent features an azide group that enables its application in click chemistry, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. It is also suitable for strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, facilitating efficient conjugation in the development of targeted therapeutics.
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