Azido-PEG6-amine is a PEG-based PROTAC linker featuring an azide functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-bearing and DBCO or BCN-containing molecules. This compound plays a crucial role in the synthesis of PROTACs, facilitating targeted protein degradation. Additionally, it serves as a non-cleavable linker in the development of antibody-drug conjugates (ADCs), providing significant versatility for researchers engaged in drug development and therapeutic applications.
Azido-PEG6-amine is a PEG-based PROTAC linker featuring an azide functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-bearing and DBCO or BCN-containing molecules. This compound plays a crucial role in the synthesis of PROTACs, facilitating targeted protein degradation. Additionally, it serves as a non-cleavable linker in the development of antibody-drug conjugates (ADCs), providing significant versatility for researchers engaged in drug development and therapeutic applications.
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