Azido-PEG6-NHS ester is a cleavable 6-unit polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis. This compound serves as a versatile linker for PROTAC applications due to its ability to participate in click chemistry through the azide group. It can facilitate copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it an essential tool for chemical biology research.
Azido-PEG6-NHS ester is a cleavable 6-unit polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis. This compound serves as a versatile linker for PROTAC applications due to its ability to participate in click chemistry through the azide group. It can facilitate copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it an essential tool for chemical biology research.
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