BAY 11-7085

Catalog No.: A12470

IκB/IKK inhibitor

BAY 11-7085

BAY 11-7085 Chemical Structure

CAS NO. 196309-76-9

BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM

Availability: In stock

Package Price Qty
10 mg

Regular Price: $70.00

Special Price $56.00

25 mg

Regular Price: $150.00

Special Price $120.00

50 mg

Regular Price: $240.00

Special Price $192.00

10mM * 1mL in DMSO

Regular Price: $55.00

Special Price $44.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Byungki Jang, .et al. The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells, Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055

Biological Activity

BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM
Targets
IκBα?phosphorylation
10 μM
In vitro DMSO 49 mg/mL (196.52 mM)
Water Insoluble
Ethanol 49 mg/mL (196.52 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.11 mL 200.54 mL 401.07 mL
0.5 mM 8.02 mL 40.11 mL 80.21 mL
1 mM 4.01 mL 20.05 mL 40.11 mL
5 mM 0.8 mL 4.01 mL 8.02 mL

*The above data is based on the productmolecular weight 249.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12470
Actions Inhibitor
CAS No. 196309-76-9
Formula C13H15NO2S
M. Wt 249.33
Purity >98%
Synonyms Bay 11-7083, BAY11-7085
SMILES CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)/C=C/C#N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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