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BB-3497

PDF Inhibitor

BB-3497 is a selective peptide deformylase (PDF) inhibitor, demonstrating a potent inhibitory effect with an IC50 of 7 nM against E. coli PDF.Ni. This compound exhibits significant antibacterial activity, particularly against gram-positive bacteria and select gram-negative pathogens, making it a valuable tool in the study of bacterial infections. In vivo studies indicate that BB-3497 effectively protects mice from systemic Staphylococcus aureus infections, highlighting its potential application in anti-bacterial research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	235784-88-0
Applications	PDF Inhibitor
Formula	C₁₆H₃₁N₃O₄
Molecular Weight	329.44
SMILES	CCCC[C@@H](C(N[C@@H](C(C)(C)C)C(N(C)C)=O)=O)CN(O)C=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.