Fig. 1 · Structure
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BB-78485
LpxC Inhibitor
BB-78485 is an LpxC metalloenzyme inhibitor that exhibits potent antibacterial activity. It effectively inhibits LpxC with an IC50 value of 160 nM, making it a valuable tool in the study of gram-negative selective antibacterials. This compound can be utilized in various research applications aimed at understanding bacterial virulence and the development of new antibacterial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 207732-11-4 |
| Applications | LpxC Inhibitor |
| Formula | C23H20N2O4S |
| Molecular Weight | 420.48 |
| SMILES | O=C([C@@H](CC1=CC=C2C=CC=CC2=C1)NS(=O)(C3=CC=C4C=CC=CC4=C3)=O)NO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.