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BCN-HS-PEG2(vcPABC-MMAE)2

Catalog No.: A41396
Drug-Linker Conjugate for ADC
BCN-HS-PEG2(vcPABC-MMAE)2 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound incorporates a cleavable linker and the microtubule inhibitor MMAE, facilitating targeted delivery of cytotoxic agents to cancer cells. BCN-HS-PEG2(vcPABC-MMAE)2 is vital for researchers involved in the development and synthesis of ADCs, enhancing therapeutic efficacy while minimizing systemic toxicity.
BCN-HS-PEG2(vcPABC-MMAE)2 2126083-82-5 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$480.00
In stock
5mg
$1,230.00
In stock
10mg
$2,015.00
In stock
25mg
$3,680.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBCN-HS-PEG2(vcPABC-MMAE)2 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound incorporates a cleavable linker and the microtubule inhibitor MMAE, facilitating targeted delivery of cytotoxic agents to cancer cells. BCN-HS-PEG2(vcPABC-MMAE)2 is vital for researchers involved in the development and synthesis of ADCs, enhancing therapeutic efficacy while minimizing systemic toxicity.
Product Information
Catalog NumA41396
FormulaC138H217N23O35S
Molecular Weight2790.40
CAS Number2126083-82-5
SMILESO=C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(OCCN(C(OCCOCCNS(=O)(NC(OC[C@@H]2[C@]3([H])CCC#CCC[C@@]32[H])=O)=O)=O)CCOC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C4)=CC=C4COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N5CCC[C@]([H])5[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C6=CC=CC=C6)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)=O)C)C(C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)N7[C@]([H])([C@@H]([C@H](C(N[C@@H]([C@@H](O)C8=CC=CC=C8)C)=O)C)OC)CCC7
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC
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