BCX-1898 is a cyclopentane derivative that functions as a selective inhibitor of influenza virus neuraminidase. It exhibits potent antiviral activity, with effective concentrations (EC50s) ranging from less than 0.01 to 21 μM against various strains of influenza A (H1N1, H3N2, H5N1) and influenza B viruses in MDCK cell cultures. Additionally, BCX-1898 demonstrates protective effects in mouse models of influenza, making it a valuable tool for research in antiviral drug development and the study of influenza virus pathogenesis.
BCX-1898 is a cyclopentane derivative that functions as a selective inhibitor of influenza virus neuraminidase. It exhibits potent antiviral activity, with effective concentrations (EC50s) ranging from less than 0.01 to 21 μM against various strains of influenza A (H1N1, H3N2, H5N1) and influenza B viruses in MDCK cell cultures. Additionally, BCX-1898 demonstrates protective effects in mouse models of influenza, making it a valuable tool for research in antiviral drug development and the study of influenza virus pathogenesis.
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