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BDM91288

AcrB efflux pump Inhibitor

BDM91288 is an orally active inhibitor of the AcrB efflux pump, derived from pyridinium piperazine. This compound demonstrates significant potential to enhance the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infections, as evidenced by mouse model studies. BDM91288 serves as a valuable tool for research focused on combating antibiotic resistance and improving the effectiveness of existing antimicrobial therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2892824-53-0
Applications	AcrB efflux pump Inhibitor
Formula	C₁₇H₂₂ClN₅
Molecular Weight	331.84
SMILES	ClC(C=C(C=C(N1CCNCC1)C=C2)C2=N3)=C3N4CCNCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.