Benzocaine-(ethyl-d5) is a deuterated form of benzocaine, targeting voltage-gated Na+ channels. This stable isotope serves as a valuable tool in pharmacokinetic studies and mechanistic research, enabling precise tracking of benzocaine metabolism and dynamics in biological systems. Its inhibitory concentration (IC50) is reported at 0.8 mM when assessed at a membrane potential of +30 mV, making it relevant for investigations into local anesthetic mechanisms and interactions.
Benzocaine-(ethyl-d5) is a deuterated form of benzocaine, targeting voltage-gated Na+ channels. This stable isotope serves as a valuable tool in pharmacokinetic studies and mechanistic research, enabling precise tracking of benzocaine metabolism and dynamics in biological systems. Its inhibitory concentration (IC50) is reported at 0.8 mM when assessed at a membrane potential of +30 mV, making it relevant for investigations into local anesthetic mechanisms and interactions.
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