Berberine HCl

Catalog No.: A10126

Berberine HCl Chemical Structure

CAS NO. 633-65-8

Berberine hydrochloride was novelly found that it has various beneficial effects on the cardiovascular system and significant anti-inflammatory activities. Berberine can effectively reduce intracellular superoxide levels in LPS-stimulated macrophages. Such a restoration of cellular redox by berberine is mediated by its selective inhibition of gp91phox expression and enhancement of SOD activity.

Availability: In stock

Package Price Qty
10 mg
$20.00
50 mg
$40.00
100 mg
$60.00
10mM * 1mL in DMSO
$50.00

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Biological Activity

Berberine hydrochloride was novelly found that it has various beneficial effects on the cardiovascular system and significant anti-inflammatory activities. Berberine can effectively reduce intracellular superoxide levels in LPS-stimulated macrophages. Such a restoration of cellular redox by berberine is mediated by its selective inhibition of gp91phox expression and enhancement of SOD activity.

Targets
In vitro DMSO 74 mg/mL (199.02 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.9 mL 134.48 mL 268.96 mL
0.5 mM 5.38 mL 26.9 mL 53.79 mL
1 mM 2.69 mL 13.45 mL 26.9 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10126
M. Wt 371.8
Formula C20H18ClNO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 633-65-8
SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-]

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