BET-IN-8

Name: BET-IN-8
Brand: Adooq Bioscience
SKU: A40492
Rating: 5 (288 reviews)

Catalog No.: A40492

BET Inhibitor

BET-IN-8 is a potent bromodomain and extraterminal (BET) inhibitor, with a Ki value of 0.83 μM and a Kd of 0.571 μM. This compound exhibits significant biological activity by ameliorating lipopolysaccharide (LPS)-induced sepsis in vivo. BET-IN-8 is valuable for research applications focused on understanding the role of BET proteins in inflammatory responses and sepsis pathophysiology.

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Biological Activity

Description	BET-IN-8 is a potent bromodomain and extraterminal (BET) inhibitor, with a Ki value of 0.83 μM and a Kd of 0.571 μM. This compound exhibits significant biological activity by ameliorating lipopolysaccharide (LPS)-induced sepsis in vivo. BET-IN-8 is valuable for research applications focused on understanding the role of BET proteins in inflammatory responses and sepsis pathophysiology.

Product Information

Catalog Num	A40492
Formula	C22H21N3O4S
Molecular Weight	423.48
CAS Number	2769893-19-6
SMILES	COC1=CC(C2=C(C(NC(SCC3=CC=CC=C3C)=N2)=O)C#N)=CC(OC)=C1OC

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