Bi-magnolignan is an inhibitor of BRD4, a key regulator involved in the recognition of acetylated lysines on histones and non-histone proteins. This compound has been shown to induce DNA damage and promote apoptosis in cancer cells, specifically inhibiting the proliferation of HCT116 cells with an IC50 value of 2.9 μM. Bi-magnolignan may serve as a valuable tool for elucidating the role of BRD4 in cancer biology and for developing novel therapeutic strategies against BRD4-dependent malignancies.
Bi-magnolignan is an inhibitor of BRD4, a key regulator involved in the recognition of acetylated lysines on histones and non-histone proteins. This compound has been shown to induce DNA damage and promote apoptosis in cancer cells, specifically inhibiting the proliferation of HCT116 cells with an IC50 value of 2.9 μM. Bi-magnolignan may serve as a valuable tool for elucidating the role of BRD4 in cancer biology and for developing novel therapeutic strategies against BRD4-dependent malignancies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
