Biotin-PEG3-SS-azide is a cleavable linker designed for antibody-drug conjugates (ADCs), featuring a three-unit polyethylene glycol (PEG) moiety. This reagent contains an azide functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups, making it a versatile tool for bioconjugation in chemical biology and therapeutic development.
Biotin-PEG3-SS-azide is a cleavable linker designed for antibody-drug conjugates (ADCs), featuring a three-unit polyethylene glycol (PEG) moiety. This reagent contains an azide functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups, making it a versatile tool for bioconjugation in chemical biology and therapeutic development.
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