Bis-PEG5-NHS ester

Catalog No.: A42586
ADC/PROTAC Linker
Bis-PEG5-NHS ester is a polyethylene glycol (PEG) based linker that targets protein degradation for the development of PROTACs (proteolysis targeting chimeras) and serves as a cleavable linker in antibody-drug conjugates (ADCs). This compound facilitates the conjugation of bioactive molecules with antibodies, enhancing the targeted delivery of therapeutic agents. Its versatile application in synthesizing both PROTACs and ADCs makes it valuable for advancing research in targeted therapies and drug delivery systems.
Grouped product items
Size Price Stock Qty
100mg
$30.00
In stock
250mg
$55.00
In stock
500mg
$85.00
In stock
1g
$135.00
In stock
5g
$340.00
In stock
10g
$510.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBis-PEG5-NHS ester is a polyethylene glycol (PEG) based linker that targets protein degradation for the development of PROTACs (proteolysis targeting chimeras) and serves as a cleavable linker in antibody-drug conjugates (ADCs). This compound facilitates the conjugation of bioactive molecules with antibodies, enhancing the targeted delivery of therapeutic agents. Its versatile application in synthesizing both PROTACs and ADCs makes it valuable for advancing research in targeted therapies and drug delivery systems.
Product Information
Catalog NumA42586
FormulaC22H32N2O13
Molecular Weight532.50
CAS Number756526-03-1
SMILESO=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
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