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Biological Activity
BMS-582949 Is a Dual Action p38 Kinase Inhibitor Well Suited To Avoid Resistance Mechanisms That Increase p38 Activation in Cells.
Targets
| p38 MAPK | ||||
| 13 nM |
| In vitro | DMSO | 79 mg/mL (194.35 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.6 mL | 123 mL | 246.01 mL |
| 0.5 mM | 4.92 mL | 24.6 mL | 49.2 mL |
| 1 mM | 2.46 mL | 12.3 mL | 24.6 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
*The above data is based on the productmolecular weight 406.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13563 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 623152-17-0 |
| Formula | C22H26N6O2 |
| M. Wt | 406.49 |
| Purity | >98% |
| Synonyms | BMS 582949 |
| SMILES | CCCNC(=O)C1=CN2C(=C1C)C(=NC=N2)NC3=C(C=CC(=C3)C(=O)NC4CC4)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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