- Ueda Y, .et al. Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems, Virus Res, 2017, May 2;235:37-48 PMID: 28322919
- Shirasaki T, .et al. Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway., Hepatology., 2014, 60(5):1519-30 PMID: 24962339
Biological Activity
Boceprevir is a protease inhibitor used as a treatment for hepatitis C genotype 1.
In vitro | DMSO | 90 mg/mL (173.18 mM) | |
Water | Insoluble | ||
Ethanol | 90 mg/mL (173.18 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.24 mL | 96.21 mL | 192.42 mL |
0.5 mM | 3.85 mL | 19.24 mL | 38.48 mL |
1 mM | 1.92 mL | 9.62 mL | 19.24 mL |
5 mM | 0.38 mL | 1.92 mL | 3.85 mL |
*The above data is based on the productmolecular weight 519.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11332 |
---|---|
Actions | Inhibitor |
CAS No. | 394730-60-0 |
Formula | C27H45N5O5 |
M. Wt | 519.7 |
Purity | >98% |
Synonyms | EBP 520, SCH 503034 |
SMILES | CC1([[email protected]@H]2[[email protected]]1[[email protected]](N(C2)C(=O)[[email protected]](C(C)(C)C)NC(=O)NC(C)(C)C)C(=O)NC(CC3CCC3)C(=O)C(=O)N)C |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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