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Boceprevir (SCH-503034)

Catalog No.: A11332

HCV Protease Inhibitor

Boceprevir (SCH-503034)

Boceprevir (SCH-503034) Chemical Structure

CAS NO. 394730-60-0

Boceprevir is a protease inhibitor used as a treatment for hepatitis C genotype 1.

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Ueda Y, .et al. Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems, Virus Res, 2017, May 2;235:37-48 PMID: 28322919
  • Shirasaki T, .et al. Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway., Hepatology., 2014, 60(5):1519-30 PMID: 24962339

Biological Activity

Boceprevir is a protease inhibitor used as a treatment for hepatitis C genotype 1.
In vitro DMSO 90 mg/mL (173.18 mM)
Water Insoluble
Ethanol 90 mg/mL (173.18 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.24 mL 96.21 mL 192.42 mL
0.5 mM 3.85 mL 19.24 mL 38.48 mL
1 mM 1.92 mL 9.62 mL 19.24 mL
5 mM 0.38 mL 1.92 mL 3.85 mL

*The above data is based on the productmolecular weight 519.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11332
Actions Inhibitor
CAS No. 394730-60-0
Formula C27H45N5O5
M. Wt 519.7
Purity >98%
Synonyms EBP 520, SCH 503034
SMILES CC1([[email protected]@H]2[[email protected]]1[[email protected]](N(C2)C(=O)[[email protected]](C(C)(C)C)NC(=O)NC(C)(C)C)C(=O)NC(CC3CCC3)C(=O)C(=O)N)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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