Fig. 1 · Structure
Documents & Downloads
Bonducellin
Efflux Pump Inhibitor
Bonducellin is a homoisoflavonoid derived from the roots of Caesalpinia digyna, acting primarily as an efflux pump inhibitor. It effectively diminishes the minimum inhibitory concentration (MIC) of ethidium bromide by eightfold against Mycobacterium smegmatis, demonstrating its potential as a valuable agent in combating mycobacterial resistance in tuberculosis. The compound's ability to target efflux pumps makes it a significant tool in the development of novel anti-TB therapies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 83162-84-9 |
| Applications | Efflux Pump Inhibitor |
| Formula | C17H14O4 |
| Molecular Weight | 282.29 |
| SMILES | O=C1/C(COC2=CC(O)=CC=C12)=C/C3=CC=C(OC)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.