Bosentan-d4 is a deuterium-labeled form of Bosentan, which acts as a competitive dual antagonist of endothelin-1 (ET) at both the ETA and ETB receptors, exhibiting Ki values of 4.7 nM and 95 nM in human smooth muscle cells, respectively. This reagent is primarily utilized in pharmacokinetic and metabolic studies, providing insights into the biological processes modulated by endothelin signaling. Its stable isotope labeling enhances the accuracy of quantification in analytical applications and research focused on cardiovascular disease mechanisms.
Bosentan-d4 is a deuterium-labeled form of Bosentan, which acts as a competitive dual antagonist of endothelin-1 (ET) at both the ETA and ETB receptors, exhibiting Ki values of 4.7 nM and 95 nM in human smooth muscle cells, respectively. This reagent is primarily utilized in pharmacokinetic and metabolic studies, providing insights into the biological processes modulated by endothelin signaling. Its stable isotope labeling enhances the accuracy of quantification in analytical applications and research focused on cardiovascular disease mechanisms.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
