BP Fluor 405 picolyl azide

Catalog No.: B11391
Fluorescent Dye
BP Fluor 405 Picolyl Azide is a fluorescent dye designed for enhanced detection in bioconjugation reactions, utilizing a copper-chelating motif to increase local Cu(I) concentrations. This innovative reagent significantly accelerates the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction rate while minimizing the required copper catalyst concentration by at least tenfold. The incorporation of the picolyl azide moiety allows for greater sensitivity in alkyne detection, making it particularly advantageous for applications involving low-abundance targets or those requiring amplified signal intensity. This makes BP Fluor 405 an essential tool for researchers focusing on advanced fluorescent labeling techniques.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBP Fluor 405 Picolyl Azide is a fluorescent dye designed for enhanced detection in bioconjugation reactions, utilizing a copper-chelating motif to increase local Cu(I) concentrations. This innovative reagent significantly accelerates the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction rate while minimizing the required copper catalyst concentration by at least tenfold. The incorporation of the picolyl azide moiety allows for greater sensitivity in alkyne detection, making it particularly advantageous for applications involving low-abundance targets or those requiring amplified signal intensity. This makes BP Fluor 405 an essential tool for researchers focusing on advanced fluorescent labeling techniques.
Product Information
Catalog NumB11391
FormulaC27H22N6O12S3
Molecular Weight718.69
CAS Number2841143-99-3
SMILES[N-]=[N+]=NCC1=NC=C(NC(CCNC(COC2=CC(S(=O)(O)=O)=C3C=CC4=C(S(=O)(O)=O)C=C(S(=O)(O)=O)C5=CC=C2C3=C45)=O)=O)C=C1
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