BRD4 Inhibitor-23

Catalog No.: A40359
BRD4 Inhibitor
BRD4 Inhibitor-23 is a selective inhibitor targeting Bromodomain-containing protein 4 (BRD4), demonstrating potent inhibition with IC50 values of 6.21 nM for BRD4 BD-1 and 1.44 nM for BRD4 BD-2. This compound is valuable for studying the role of BRD4 in various cellular processes, including transcriptional regulation and cell cycle progression. Its applications extend to research in cancer biology and epigenetic regulation, making it a powerful tool for exploring therapeutic interventions.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBRD4 Inhibitor-23 is a selective inhibitor targeting Bromodomain-containing protein 4 (BRD4), demonstrating potent inhibition with IC50 values of 6.21 nM for BRD4 BD-1 and 1.44 nM for BRD4 BD-2. This compound is valuable for studying the role of BRD4 in various cellular processes, including transcriptional regulation and cell cycle progression. Its applications extend to research in cancer biology and epigenetic regulation, making it a powerful tool for exploring therapeutic interventions.
Product Information
Catalog NumA40359
FormulaC22H19F2N3O4S
Molecular Weight459.47
CAS Number2760307-53-5
SMILESCCS(=O)(CC1=CC(N2C=C(C3=C2C=CNC3=O)C)=C(N=C1)OC4=C(C=C(C=C4)F)F)=O
Useful Calculator

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