BS-181 hydrochloride

Catalog No.: A21988

CDK7 inhibitor

BS-181 hydrochloride

BS-181 hydrochloride Chemical Structure

CAS NO. 1397219-81-6

BS-181 hydrochloride is a highly selective CDK7 inhibitor with IC50 of 21 nM, and > 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BS-181 hydrochloride is a highly selective CDK7 inhibitor with IC50 of 21 nM, and > 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
In vitro (25°C) DMSO 81 mg/mL (194.24 mM)
Water 3 mg/mL (7.19 mM)
Ethanol Warmed: 22 mg/mL (52.75 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.98 mL 119.91 mL 239.81 mL
0.5 mM 4.8 mL 23.98 mL 47.96 mL
1 mM 2.4 mL 11.99 mL 23.98 mL
5 mM 0.48 mL 2.4 mL 4.8 mL

*The above data is based on the productmolecular weight 416.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21988
Actions Inhibitor
CAS No. 1397219-81-6
Formula C22H33ClN6
M. Wt 416.99
Solubility DMSO
Purity >98%
Synonyms BS181, BS 181
SMILES CC(C1=C(N=C(C=C2NCC3=CC=CC=C3)NCCCCCCN)N2N=C1)C.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy BS-181 hydrochloride | BS-181 hydrochloride Supplier | purchase | cost | manufacturer | order | distributor | buy 1397219-81-6| 1397219-81-6 Supplier | purchase 1397219-81-6 | 1397219-81-6 cost | 1397219-81-6 manufacturer | order 1397219-81-6 | 1397219-81-6 distributor
Rewards