Fig. 1 · Structure
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BTZ-N3
DprE1 Inhibitor
BTZ-N3 is a potent reversible and noncovalent inhibitor of decaprenylphosphoryl-β-d-ribose 2′ oxidase (DprE1), a key enzyme in mycobacterial cell wall synthesis. This compound exhibits significant anti-tuberculosis activity, making it valuable for research focused on combating mycobacterial infections. Its inhibitory effects on DprE1 contribute to the exploration of new therapeutic strategies against tuberculosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1839081-05-8 |
| Applications | DprE1 Inhibitor |
| Formula | C17H16F3N5O3S |
| Molecular Weight | 427.40 |
| SMILES | O=C1N=C(N(CC2)CCC32OC[C@H](C)O3)SC4=C(N=[N+]=[N-])C=C(C(F)(F)F)C=C14 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.