cAIMP (Cyclic Adenosine-Inosine Monophosphate) functions as a synthetic cyclic dinucleotide that activates immune response pathways by engaging IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). This compound is capable of inducing the secretion of interferons and pro-inflammatory cytokines in vitro in human blood, demonstrating an EC50 of 6.4 μmol/L. cAIMP serves as a valuable tool for research focused on innate immune signaling and inflammation responses.
cAIMP (Cyclic Adenosine-Inosine Monophosphate) functions as a synthetic cyclic dinucleotide that activates immune response pathways by engaging IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). This compound is capable of inducing the secretion of interferons and pro-inflammatory cytokines in vitro in human blood, demonstrating an EC50 of 6.4 μmol/L. cAIMP serves as a valuable tool for research focused on innate immune signaling and inflammation responses.
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