CAMK1D-IN-1 (compound I) is a CAMK1D inhibitor that targets tumor cells resistant to cytotoxic T lymphocyte (CTL)-mediated killing. CAMK1D suppresses CTL-induced death receptor signaling and apoptosis through caspase inhibition, making it a promising therapeutic target for PD-L1-refractory tumors.
CAMK1D-IN-1 (compound I) is a CAMK1D inhibitor that targets tumor cells resistant to cytotoxic T lymphocyte (CTL)-mediated killing. CAMK1D suppresses CTL-induced death receptor signaling and apoptosis through caspase inhibition, making it a promising therapeutic target for PD-L1-refractory tumors.
Product Information
Catalog Num
A22128
Formula
C18H19N5
Molecular Weight
305.38
CAS Number
404828-08-6
SMILES
CC1=CC(NC2=NC(C3=CC=CC=C3)=NC4=C2CCCC4)=NN1
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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