Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent endonuclease (CEN), which plays a critical role in viral RNA synthesis. This compound effectively inhibits multiple strains of the influenza virus while exhibiting lower cytotoxicity and favorable in vivo pharmacokinetic and pharmacodynamic profiles. Additionally, Cap-dependent endonuclease-IN-10 demonstrates enhanced hepatic microsomal stability, making it valuable for research applications focused on viral infections, including influenza A, B, and C.
Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent endonuclease (CEN), which plays a critical role in viral RNA synthesis. This compound effectively inhibits multiple strains of the influenza virus while exhibiting lower cytotoxicity and favorable in vivo pharmacokinetic and pharmacodynamic profiles. Additionally, Cap-dependent endonuclease-IN-10 demonstrates enhanced hepatic microsomal stability, making it valuable for research applications focused on viral infections, including influenza A, B, and C.
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