Melatonin-d7 is a stable isotope-labeled form of melatonin, primarily known for its role as a hormone that activates melatonin receptors. This compound exhibits significant antioxidative and anti-inflammatory effects, contributing to sleep regulation. Additionally, melatonin-d7 is identified as a selective inhibitor of ATF-6, inducing apoptosis in human hepatoma cells through the downregulation of COX-2. In research applications, it has been shown to mitigate palmitic acid-induced apoptosis in mouse granulosa cells by modulating endoplasmic reticulum stress.
Melatonin-d7 is a stable isotope-labeled form of melatonin, primarily known for its role as a hormone that activates melatonin receptors. This compound exhibits significant antioxidative and anti-inflammatory effects, contributing to sleep regulation. Additionally, melatonin-d7 is identified as a selective inhibitor of ATF-6, inducing apoptosis in human hepatoma cells through the downregulation of COX-2. In research applications, it has been shown to mitigate palmitic acid-induced apoptosis in mouse granulosa cells by modulating endoplasmic reticulum stress.
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