Fig. 1 · Structure
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CB 168
IleRS Inhibitor
CB 168 is a selective inhibitor of isoleucyl-tRNA synthetase (IleRS). It demonstrates potent activity in blocking aminoacylation, thereby interfering with protein synthesis. This compound is valuable for biochemical studies aimed at understanding IleRS function and its role in various cellular processes. Additionally, CB 168 may have therapeutic implications in the development of antimicrobial agents targeting tRNA synthetases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1241942-59-5 |
| Applications | IleRS Inhibitor |
| Formula | C20H30N6O7S |
| Molecular Weight | 498.55 |
| SMILES | CC[C@H](C)[C@H](N)C(NS(OC[C@H]([C@H]([C@H]1O)O)O[C@H]1CCN2N=C(C3=CC=CC=C3)N=N2)(=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.