cCBD-LL37 is a chimeric antimicrobial peptide featuring a collagen-binding domain (cCBD), enhancing its retention on collagen matrices. This peptide exhibits potent antimicrobial activity and maintains structural stability across a range of ionic strengths and pH levels (5.5-8). Its binding to collagen involves a combination of specific and non-specific interactions, initiated by long-range electrostatic forces. cCBD-LL37 is primarily utilized in research involving collagen-based biomaterials, such as wound dressings, where enhanced bacterial resistance and retention are critical.
cCBD-LL37 is a chimeric antimicrobial peptide featuring a collagen-binding domain (cCBD), enhancing its retention on collagen matrices. This peptide exhibits potent antimicrobial activity and maintains structural stability across a range of ionic strengths and pH levels (5.5-8). Its binding to collagen involves a combination of specific and non-specific interactions, initiated by long-range electrostatic forces. cCBD-LL37 is primarily utilized in research involving collagen-based biomaterials, such as wound dressings, where enhanced bacterial resistance and retention are critical.
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