Fig. 1 · Structure
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Cefsulodin sodium hydrate
mPTPB Inhibitor
Cefsulodin sodium hydrate is a third-generation β-lactam antibiotic that primarily targets penicillin-binding proteins (PBPs) to inhibit cell wall synthesis through competitive inhibition of cross-linking and transpeptidation of peptidoglycan. Additionally, it serves as a potent mPTPB inhibitor, effectively targeting the virulent tyrosine phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM. This compound is valuable for research involving antibiotic resistance mechanisms and the study of mycobacterial infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1426397-23-0 |
| Applications | mPTPB Inhibitor |
| Formula | C22H19N4O8S2.Na.XH2O |
| Molecular Weight | 554.53 (Anhydrous) |
| Synonyms | SCE-129 sodium hydrate |
| SMILES | [O-]C(C1=C(C[N+]2=CC=C(C(N)=O)C=C2)CS[C@@]([C@@H]3NC([C@@H](C4=CC=CC=C4)S(=O)(O[Na])=O)=O)([H])N1C3=O)=O.[F,Cl,Br,I].O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.