- Cat. No.
- A74629
Sob-AM2
Sob-AM2 is a high-affinity substrate for fatty acid amide hydrolase (FAAH), exhibiting a Km of 1.3 μM and demonstrating effective blood-brain barrier permeability. This compound facilitates elevated delivery of Sobetirome to the central nervous system while minimizing peripheral exposure, thus activating central thyroid hormone receptor β (TRβ). Additionally, Sob-AM2 has been shown to protect against myelin and axon degeneration in models of experimental autoimmune encephalomyelitis (EAE), making it a valuable tool for investigating neuroprotective mechanisms and central nervous system disorders.