Cevipabulin fumarate

Catalog No.: A21617

Cevipabulin fumarate

Cevipabulin fumarate Chemical Structure

CAS NO. 849550-67-0

Cevipabulin fumarate (TTI-237 fumarate) is an oral, microtubule-active, antitumor compound and inhibits the binding of [3H]NSC 49842 to tubulin, with an IC50 of 18-40 nM for cytotoxicity in human tumor cell line.

Availability: In stock

Package Price Qty
5 mg
$151.00
10 mg
$260.00
50 mg
$773.00
100 mg
$1,546.00
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Biological Activity

Cevipabulin fumarate (TTI-237 fumarate) is an oral, microtubule-active, antitumor compound and inhibits the binding of [3H]NSC 49842 to tubulin, with an IC50 of 18-40 nM for cytotoxicity in human tumor cell line.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.21 mL 86.07 mL 172.15 mL
0.5 mM 3.44 mL 17.21 mL 34.43 mL
1 mM 1.72 mL 8.61 mL 17.21 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 580.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21617
CAS No. 849550-67-0
Formula C22H22ClF5N6O5
M. Wt 580.89
Purity >98%
Synonyms TTI-237 fumarate, TTI237, TTI 237
SMILES C[[email protected]@H](C(F)(F)F)NC1=C(C2=C(F)C=C(OCCCNC)C=C2F)C(Cl)=NC3=NC=NN13.O=C(O)/C=C/C(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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