Cevipabulin (TTI-237)

Catalog No.: A12591

Cevipabulin (TTI-237)

Cevipabulin (TTI-237) Chemical Structure

CAS NO. 849550-05-6

Cevipabulin (TTI-237), an antimicrotubule agent, is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity. With a novel mechanism of action distinct from the action of other vinca alkaloid compounds, TTI-237 specifically binds to tubulin at the vinca site, and promotes the polymerization of tubulin into microtubules.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
25 mg
$400.00
50 mg
$680.00
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Biological Activity

Cevipabulin (TTI-237), an antimicrotubule agent, is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity. With a novel mechanism of action distinct from the action of other vinca alkaloid compounds, TTI-237 specifically binds to tubulin at the vinca site, and promotes the polymerization of tubulin into microtubules.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.51 mL 107.57 mL 215.14 mL
0.5 mM 4.3 mL 21.51 mL 43.03 mL
1 mM 2.15 mL 10.76 mL 21.51 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 464.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12591
CAS No. 849550-05-6
Formula C18H18ClF5N6O
M. Wt 464.82
Purity >98%
Synonyms TTI237, D06576
SMILES C[[email protected]@H](C(F)(F)F)NC1=C(C(=NC2=NC=NN12)Cl)C3=C(C=C(C=C3F)OCCCNC)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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