Chitin Synthase Inhibitor 2 selectively targets chitin synthase, demonstrating potent inhibitory effects with an IC50 of 0.09 mM and a Ki of 0.12 mM. This compound exhibits significant antimicrobial activity in vitro and can enhance the effects of fluconazole and polyoxin B, making it a valuable tool for investigating chitin biosynthesis and potential applications in antifungal research.
Chitin Synthase Inhibitor 2 selectively targets chitin synthase, demonstrating potent inhibitory effects with an IC50 of 0.09 mM and a Ki of 0.12 mM. This compound exhibits significant antimicrobial activity in vitro and can enhance the effects of fluconazole and polyoxin B, making it a valuable tool for investigating chitin biosynthesis and potential applications in antifungal research.
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