Fig. 1 · Structure
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Cidofovir dihydrate
CMV Inhibitor
Cidofovir dihydrate is an acyclic monophosphate nucleotide analogue that targets cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. This compound exhibits significant antiviral activity, making it valuable for research on CMV-related diseases, including AIDS-associated cytomegalovirus retinitis and certain cancers. Additionally, cidofovir dihydrate possesses anti-orthopoxvirus and anti-variola properties, supporting its utility in the study of various viral infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 149394-66-1 |
| Applications | CMV Inhibitor |
| Formula | C8H18N3O8P |
| Molecular Weight | 315.22 |
| Synonyms | GS 0504 dihydrate; HPMPC dihydrate; (S)-HPMPC dihydrate |
| SMILES | OC[C@@H](OCP(O)(O)=O)CN1C=CC(N)=NC1=O.O.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.