Fig. 1 · Structure
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Cidofovir sodium
CMV Inhibitor
Cidofovir sodium is an acyclic monophosphate nucleotide analogue that acts as a selective inhibitor of cytomegalovirus (CMV) replication by targeting viral DNA polymerase. This compound exhibits significant antiviral activity and induces apoptosis, making it valuable for research into AIDS-related CMV retinitis, herpes infection, and cancer therapies. Additionally, cidofovir sodium demonstrates anti-orthopoxvirus and anti-variola properties, further expanding its utility in virology studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 127749-27-3 |
| Applications | CMV Inhibitor |
| Formula | C8H12N3Na2O6P |
| Molecular Weight | 323.15 |
| Synonyms | GS 0504 sodium; HPMPC sodium; (S)-HPMPC sodium |
| SMILES | OC[C@@H](OCP(O[Na])(O[Na])=O)CN1C=CC(N)=NC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.